HI Big Rob.
A well sorted holley is hard to beat as far as performance and economy is concerned but I am 44years old and have worked on cars all my adult life and barely know the basics of holley tuning.
To me a burnt set of points or a blown fuel pump diaphragm is no better or worse than a fried ignition module or a failing water temp sender.
If you are comfortable doing what you know stick with it.
There are a lot of myths about modern efi systems but at the end of the day reliability of any system is a product of its builders skill and attention to detail.
A good example of this is when a friend of mine replaced the electronic ignition module on his 6cyl vb commodore without using heat sink grease and couldn't understand why it would shut down when it got hot.
I like efi but I also appreciate the simple elegance of a well sorted carby .